Cecilia, a Mexican immigrant, learns from her doctor that she has a benign cyst that will disappear on its own. When the doctor mentions that sexual intercourse could speed up the process, she realizes she hasn't had sex in five years. That night, her friend Josselyn takes her to a dive bar to "fill her prescription." But when the two women go home with some suitors, Cecilia will make a surprising discovery of what's really been ailing her.

El Remedio premiered at OutfestLA in 2019. It also played at the Oaxaca Film Festival among a handful of other festivals before the pandemic hit. It was licensed by HBO in 2021 for HBO Max and HBO Latino.